Resting-State Functional Connectivity in Psychiatric Disorders
نویسندگان
چکیده
منابع مشابه
Resting-State Functional Connectivity in Psychiatric Disorders.
The idea that serious mental illnesses, such as autism and schizophrenia, result fromabnormalconnectivityamong largescale brain networks is gaining widespread acceptance. Efforts to test hypotheses of dysconnectivity have historically been hindered by tools with insufficient spatial resolution to investigatehumanbrain connectivity in vivo and an incomplete understanding of the large-scaleorgani...
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Ongoing debate exists within the resting-state functional MRI (fMRI) literature over how intrinsic connectivity is altered in the autistic brain, with reports of general over-connectivity, under-connectivity, and/or a combination of both. Classifying autism using brain connectivity is complicated by the heterogeneous nature of the condition, allowing for the possibility of widely variable conne...
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Psychiatric research has been hampered by an explanatory gap between psychiatric symptoms and their neural underpinnings, which has resulted in poor treatment outcomes. This situation has prompted us to shift from symptom-based diagnosis to data-driven diagnosis, aiming to redefine psychiatric disorders as disorders of neural circuitry. Promising candidates for data-driven diagnosis include res...
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ژورنال
عنوان ژورنال: JAMA Psychiatry
سال: 2015
ISSN: 2168-622X
DOI: 10.1001/jamapsychiatry.2015.0484